In that situation you're talking about someone who I really feel sorry for since they fell for a con artist that has no means let alone intention of bringing meaningful recooperation to those depressed areas.
I would also say a lot of people in those areas DO overlap with the types that are anti-Muslim, anti-immigrant, and anti-LGBT in large part because of lack of exposure. Trump took that fear, that anger, and that ignorance and beat his drum pretty loudly on it.
And I don't believe that you are voting against yourself to vote in favor of equality and respect for people that are different than you. The fact that it can be so easily framed as us vs them is very much a part of the problem.
And I'm sure Nathan wasn't trying to call me out. If he knew anything about me he'd know I have much more contempt for the rich than poor white people.